A validated high-performance liquid chromatographic method for the determination of levodopa in rat plasma & its application in pharmacokinetic studies

Abstract

Levodopa (l-dopa), the metabolic precursor of dopamine, has primarily been used for the treatment of Parkinson's disease (PD). A reversed phase high performance liquid chromatography (RP-HPLC) method with UV-detection at room temperature has been developed for analysis of levodopa. The method entailed direct injection of rat plasma sample after… (More)

Topics

8 Figures and Tables

Cite this paper

@article{Ahmad2012AVH, title={A validated high-performance liquid chromatographic method for the determination of levodopa in rat plasma & its application in pharmacokinetic studies}, author={Mohd Zulhelmy Ahmad and Khuriah Abdul Hamid and Tommy Julianto Bustami Effendi}, journal={2012 IEEE Symposium on Business, Engineering and Industrial Applications}, year={2012}, pages={134-139} }