A urokinase receptor-associated protein with specific collagen binding properties.

@article{Behrendt2000AUR,
  title={A urokinase receptor-associated protein with specific collagen binding properties.},
  author={Niels Behrendt and Ole N Jensen and Lars Henning Engelholm and Ejvind M\ortz and Matthias Mann and Keld Dan\o},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 3},
  pages={1993-2002}
}
The plasminogen activation cascade system, directed by urokinase and the urokinase receptor, plays a key role in extracellular proteolysis during tissue remodeling. To identify molecular interaction partners of these trigger proteins on the cell, we combined covalent protein cross-linking with mass spectrometry based methods for peptide mapping and primary structure analysis of electrophoretically isolated protein conjugates. A specific tri-molecular complex was observed upon addition of pro… CONTINUE READING