A unique pattern of photoreceptor degeneration in cyclin D1 mutant mice.

@article{Ma1998AUP,
  title={A unique pattern of photoreceptor degeneration in cyclin D1 mutant mice.},
  author={Caldwell Ma and David S. Papermaster and Constance L. Cepko},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 17},
  pages={9938-43}
}
Cyclin D1-deficient mice have small eyes with thin retinas. We observed that there was a lower level of retinal cell proliferation and a unique pattern of photoreceptor cell death. Death was first observed in scattered clusters of cells in the retina. It then appeared to spread from these few cells to nearby photoreceptors, eventually producing extensive… CONTINUE READING