A unique nodavirus with novel features: mosinovirus expresses two subgenomic RNAs, a capsid gene of unknown origin, and a suppressor of the antiviral RNA interference pathway.

@article{Schuster2014AUN,
  title={A unique nodavirus with novel features: mosinovirus expresses two subgenomic RNAs, a capsid gene of unknown origin, and a suppressor of the antiviral RNA interference pathway.},
  author={Susan Schuster and Florian Zirkel and Andreas Kurth and Koen W. R. van Cleef and Christian Drosten and Ronald P van Rij and Sandra Junglen},
  journal={Journal of virology},
  year={2014},
  volume={88 22},
  pages={13447-59}
}
UNLABELLED Insects are a reservoir for many known and novel viruses. We discovered an unknown virus, tentatively named mosinovirus (MoNV), in mosquitoes from a tropical rainforest region in Côte d'Ivoire. The MoNV genome consists of two segments of positive-sense RNA of 2,972 nucleotides (nt) (RNA 1) and 1,801 nt (RNA 2). Its putative RNA-dependent RNA polymerase shares 43% amino acid identity with its closest relative, that of the Pariacoto virus (family Nodaviridae). Unexpectedly, for the… CONTINUE READING
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