A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients.

@article{Roessler2010AUM,
  title={A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients.},
  author={Stephanie Roessler and Hu-Liang Jia and Anuradha S. Budhu and Marshonna Forgues and Qing-hai Ye and Sheila Brennan Fisher and Snorri Thorgeirsson and Zhongtang Sun and Zhao-you Tang and Lunxiu Qin and Xin Wei Wang},
  journal={Cancer research},
  year={2010},
  volume={70 24},
  pages={
          10202-12
        }
}
Metastasis-related recurrence often occurs in hepatocellular carcinoma (HCC) patients who receive curative therapies. At present, it is challenging to identify patients with high risk of recurrence, which would warrant additional therapies. In this study, we sought to analyze a recently developed metastasis-related gene signature for its utility in predicting HCC survival, using 2 independent cohorts consisting of a total of 386 patients who received radical resection. Cohort 1 contained 247… CONTINUE READING

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