A unique chromatin complex occupies young α-satellite arrays of human centromeres

@inproceedings{Henikoff2015AUC,
  title={A unique chromatin complex occupies young α-satellite arrays of human centromeres},
  author={Jorja G. Henikoff and Jitendra Kumar Thakur and Sivakanthan Kasinathan and Steven Henikoff},
  booktitle={Science Advances},
  year={2015}
}
The intractability of homogeneous α-satellite arrays has impeded understanding of human centromeres. Artificial centromeres are produced from higher-order repeats (HORs) present at centromere edges, although the exact sequences and chromatin conformations of centromere cores remain unknown. We use high-resolution chromatin immunoprecipitation (ChIP) of centromere components followed by clustering of sequence data as an unbiased approach to identify functional centromere sequences. We find that… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 12 times over the past 90 days. VIEW TWEETS
17 Extracted Citations
47 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 17 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 47 references

Similar Papers

Loading similar papers…