A unique 2-sulfated {beta}-galactan from the egg jelly of the sea urchin Glyptocidaris crenularis: conformation flexibility versus induction of the sperm acrosome reaction.

@article{Castro2009AU2,
  title={A unique 2-sulfated \{beta\}-galactan from the egg jelly of the sea urchin Glyptocidaris crenularis: conformation flexibility versus induction of the sperm acrosome reaction.},
  author={Michelle O. Castro and Vitor H Pomin and Livia L Santos and Ana-Cristina E. S. Vilela-Silva and Noritaka Hirohashi and Laercio Pol-Fachin and Hugo Verli and Paulo A. S. Mour{\~a}o},
  journal={The Journal of biological chemistry},
  year={2009},
  volume={284 28},
  pages={18790-800}
}
Sulfated polysaccharides from the egg jelly of sea urchins act as species-specific inducers of the sperm acrosome reaction, which is a rare molecular mechanism of carbohydrate-induced signal-transduction event in animal cells. The sea urchin polysaccharides differ in monosaccharide composition (l-fucose or l-galactose), glycosylation, and sulfation sites, but they are always in the alpha-anomeric configuration. Herein, structural analysis of the polysaccharide from the sea urchin Glyptocidaris… CONTINUE READING