A-type dimeric epigallocatechin-3-gallate (EGCG) is a more potent inhibitor against the formation of insulin amyloid fibril than EGCG monomer.

@article{Nie2016AtypeDE,
  title={A-type dimeric epigallocatechin-3-gallate (EGCG) is a more potent inhibitor against the formation of insulin amyloid fibril than EGCG monomer.},
  author={Rong-Zu Nie and Wei Zhu and Jin-Ming Peng and Zhen-zhen Ge and Chunmei Li},
  journal={Biochimie},
  year={2016},
  volume={125},
  pages={204-12}
}
Because fibrillary protein aggregates is regarded to be closely associated with many diseases such as Alzheimer's disease, diabetes, and Parkinson's disease, growing interest and researches have been focused on finding potential fibrillation inhibitors. In the present study, the inhibitory effects of epigallocatechin-3-gallate (EGCG) and A-type dimeric… CONTINUE READING