A type III polyketide synthase from Wachendorfia thyrsiflora and its role in diarylheptanoid and phenylphenalenone biosynthesis

@article{Brand2006ATI,
  title={A type III polyketide synthase from Wachendorfia thyrsiflora and its role in diarylheptanoid and phenylphenalenone biosynthesis},
  author={Silke Brand and Dirk H{\"o}lscher and Angelika Schierhorn and Ale{\vs} Svato{\vs} and Joachim Schr{\"o}der and Bernd Schneider},
  journal={Planta},
  year={2006},
  volume={224},
  pages={413-428}
}
Chalcone synthase (CHS) related type III plant polyketide synthases (PKSs) are likely to be involved in the biosynthesis of diarylheptanoids (e.g. curcumin and polycyclic phenylphenalenones), but no such activity has been reported. Root cultures from Wachendorfia thyrsiflora (Haemodoraceae) are a suitable source to search for such enzymes because they synthesize large amounts of phenylphenalenones, but no other products that are known to require CHSs or related enzymes (e.g. flavonoids or… CONTINUE READING

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