A type II ribonuclease H from Leishmania mitochondria: an enzyme essential for the growth of the parasite.

@article{Misra2005ATI,
  title={A type II ribonuclease H from Leishmania mitochondria: an enzyme essential for the growth of the parasite.},
  author={Smita Misra and Jabbar Bennett and Yeshitila N Friew and Junaid Abdulghani and Charletha V Irvin-Wilson and Manish Kumar Tripathi and Shauntae Williams and Minu Chaudhuri and Gautam Chaudhuri},
  journal={Molecular and biochemical parasitology},
  year={2005},
  volume={143 2},
  pages={135-45}
}
Replication of kDNA in the mitochondrion of the kinetoplastid protozoan is an essential process. One of the proteins that may be required for the kDNA replication is the ribonuclease H (RNase H; EC 3.1.26.4). We have identified four distinct ribonuclease H genes in Leishmania, one type I (LRNase HI) and three type II (LRNase HIIA, LRNase HIIB and LRNase… CONTINUE READING