A type I cell-specific protein is a biochemical marker of epithelial injury in a rat model of pneumonia.

@article{McElroy1995ATI,
  title={A type I cell-specific protein is a biochemical marker of epithelial injury in a rat model of pneumonia.},
  author={Michael C McElroy and J F Pittet and See Hashimoto and Lennell Allen and Jeanine P. Wiener-Kronish and Leland G. Dobbs},
  journal={The American journal of physiology},
  year={1995},
  volume={268 2 Pt 1},
  pages={L181-6}
}
In this study we determined whether the alveolar fluid content of a specific epithelial type I cell protein, rTI40, can be used as a biochemical marker for lung injury. A model of alveolar epithelial injury was developed by instilling Pseudomonas aeruginosa bacteria (PA103) into the airspaces of anesthetized, ventilated rats. After 6 h, the alveolar fluid content of rTI40 from PA103-treated rats was increased over 80-fold in comparison to alveolar fluid from control rats (P < 0.05). This… CONTINUE READING

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