A type 1 diabetes-related protein from wheat (Triticum aestivum). cDNA clone of a wheat storage globulin, Glb1, linked to islet damage.

@article{MacFarlane2003AT1,
  title={A type 1 diabetes-related protein from wheat (Triticum aestivum). cDNA clone of a wheat storage globulin, Glb1, linked to islet damage.},
  author={Amanda J MacFarlane and Karolina Maria Burghardt and John A. Kelly and Tuula T. Simell and Olli Simell and Illimar Altosaar and Fraser W. Scott},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 1},
  pages={54-63}
}
The development of autoimmune type 1 diabetes involves complex interactions among several genes and environmental agents. Human patients with type 1 diabetes show an unusually high frequency of wheat gluten-sensitive enteropathy; T-cell response to wheat proteins is increased in some patients, and high concentrations of wheat antibodies in blood have been reported. In both major models of spontaneous type 1 diabetes, the BioBreeding (BB) rat and non-obese diabetic mouse, at least half of the… CONTINUE READING

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Human patients with type 1 diabetes show an unusually high frequency of wheat gluten - sensitive enteropathy ; T - cell response to wheat proteins is increased in some patients , and high concentrations of wheat antibodies in blood have been reported .
Human patients with type 1 diabetes show an unusually high frequency of wheat gluten - sensitive enteropathy ; T - cell response to wheat proteins is increased in some patients , and high concentrations of wheat antibodies in blood have been reported .
A major limitation in understanding how wheat or other dietary antigens affect type 1 diabetes has been the difficulty in identifying specific diabetes - related dietary proteins .
A major limitation in understanding how wheat or other dietary antigens affect type 1 diabetes has been the difficulty in identifying specific diabetes - related dietary proteins .
A major limitation in understanding how wheat or other dietary antigens affect type 1 diabetes has been the difficulty in identifying specific diabetes - related dietary proteins .
A major limitation in understanding how wheat or other dietary antigens affect type 1 diabetes has been the difficulty in identifying specific diabetes - related dietary proteins .
A major limitation in understanding how wheat or other dietary antigens affect type 1 diabetes has been the difficulty in identifying specific diabetes - related dietary proteins .
A major limitation in understanding how wheat or other dietary antigens affect type 1 diabetes has been the difficulty in identifying specific diabetes - related dietary proteins .
A major limitation in understanding how wheat or other dietary antigens affect type 1 diabetes has been the difficulty in identifying specific diabetes - related dietary proteins .
In both major models of spontaneous type 1 diabetes , the BioBreeding ( BB ) rat and non - obese diabetic mouse , at least half of the cases are diet - related .
In both major models of spontaneous type 1 diabetes , the BioBreeding ( BB ) rat and non - obese diabetic mouse , at least half of the cases are diet - related .
In both major models of spontaneous type 1 diabetes , the BioBreeding ( BB ) rat and non - obese diabetic mouse , at least half of the cases are diet - related .
A major limitation in understanding how wheat or other dietary antigens affect type 1 diabetes has been the difficulty in identifying specific diabetes - related dietary proteins .
A major limitation in understanding how wheat or other dietary antigens affect type 1 diabetes has been the difficulty in identifying specific diabetes - related dietary proteins .
A major limitation in understanding how wheat or other dietary antigens affect type 1 diabetes has been the difficulty in identifying specific diabetes - related dietary proteins .
In both major models of spontaneous type 1 diabetes , the BioBreeding ( BB ) rat and non - obese diabetic mouse , at least half of the cases are diet - related .
In both major models of spontaneous type 1 diabetes , the BioBreeding ( BB ) rat and non - obese diabetic mouse , at least half of the cases are diet - related .
In both major models of spontaneous type 1 diabetes , the BioBreeding ( BB ) rat and non - obese diabetic mouse , at least half of the cases are diet - related .
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