A two-step strategy for detecting differential gene expression in cDNA microarray data

@article{Lu2004ATS,
  title={A two-step strategy for detecting differential gene expression in cDNA microarray data},
  author={Yan Lu and Jun Zhu and Pengyuan Y Liu},
  journal={Current Genetics},
  year={2004},
  volume={47},
  pages={121-131}
}
A mixed-model approach is proposed for identifying differential gene expression in cDNA microarray experiments. This approach is implemented by two interconnected steps. In the first step, we choose a subset of genes that are potentially expressed differentially among treatments with a loose criterion. In the second step, these potential genes are used for further analyses and data-mining with a stringent criterion, in which differentially expressed genes (DEGs) are confirmed and some… CONTINUE READING

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Statistical methods for identifying differentially expressed genes in replicated cDNA microarray experiments

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  • Stat Sin
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