A two-step mechanism for myotome formation in chick.

  title={A two-step mechanism for myotome formation in chick.},
  author={Jerome Gros and Martin Scaal and Christophe Marcelle},
  journal={Developmental cell},
  volume={6 6},
The study of the morphogenetic cell movements underlying myotome formation in the chick embryo has led to the emergence of highly controversial models. Here we report a real-time cell lineage analysis of myotome development using electroporation of a GFP reporter in newly formed chick somites. Confocal analysis of cell movements demonstrates that myotome formation involves two sequential steps. In a first phase, incremental myotome growth results from a contribution of myocytes derived solely… CONTINUE READING