A two-phase binning algorithm using l-mer frequency on groups of non-overlapping reads

Metagenomics is the study of genetic materials derived directly from complex microbial samples, instead of from culture. One of the crucial steps in metagenomic analysis, referred to as “binning”, is to separate reads into clusters that represent genomes from closely related organisms. Among the existing binning methods, unsupervised methods base the… (More)