A two-dimensional electrophoretic map of human mitochondrial proteins from immortalized lymphoblastoid cell lines: a prerequisite to study mitochondrial disorders in patients.

@article{Xie2005ATE,
  title={A two-dimensional electrophoretic map of human mitochondrial proteins from immortalized lymphoblastoid cell lines: a prerequisite to study mitochondrial disorders in patients.},
  author={Jing Xie and Sandra Techritz and Sophie Haebel and Anke Horn and Heidemarie Neitzel and Joachim Klose and Markus Schuelke},
  journal={Proteomics},
  year={2005},
  volume={5 11},
  pages={2981-99}
}
Mitochondrial diseases may be caused by numerous mutations that alter proteins of the respiratory chain and of other metabolic pathways in the mitochondrium. For clinicians this disease group poses a considerable diagnostic challenge due to ambiguous genotype-phenotype relationships. Until now, only 30% of the mitochondriopathies can be diagnosed at the… CONTINUE READING