A two-component regulatory system playing a critical role in plant pathogens and endosymbionts is present in Brucella abortus and controls cell invasion and virulence.

Abstract

Two mutants showing increased sensitivity to polycations and surfactants were obtained by transposon mutagenesis of virulent Brucella abortus 2308 Nalr. These mutants showed no obvious in vitro growth defects and produced smooth-type lipopolysaccharides. However, they hardly multiplied or persisted in mouse spleens, displayed reduced invasiveness in… (More)

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@article{SolaLanda1998ATR, title={A two-component regulatory system playing a critical role in plant pathogens and endosymbionts is present in Brucella abortus and controls cell invasion and virulence.}, author={Alberto Sola-Landa and Javier Pizarro-Cerd{\'a} and M. J. Grill{\'o} and E. Moreno and Ignacio Moriy{\'o}n and J. M. Blasco and J P Gorvel and Ignacio L{\'o}pez-Go{\~n}i}, journal={Molecular microbiology}, year={1998}, volume={29 1}, pages={125-38} }