A two-compartment model for zinc in humans.

  title={A two-compartment model for zinc in humans.},
  author={W. S. Watson and Kathryn G. Mitchell and Thomas D B Lyon and N Ortuzar Kerr},
  journal={Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements},
  volume={13 3},
The oral absorption of zinc, from a test meal of minced beef, mashed potatoes and peas, have been measured in 19 healthy adults using the radiotracer 65Zn. The oral absorption, expressed as a percentage of the administered dose, was 20 +/- 5% (mean +/- 1 SD) in good agreement with previous results. In a subset of 9 subjects, tracer retention in whole body and whole blood was followed out to one year. The data were fitted to a simple two compartment model yielding total body zinc (TBZn), the… CONTINUE READING