A two‐component signal transduction system involved in nickel sensing in the cyanobacterium Synechocystis sp. PCC 6803

@article{LpezMaury2002ATS,
  title={A two‐component signal transduction system involved in nickel sensing in the cyanobacterium Synechocystis sp. PCC 6803},
  author={Luis L{\'o}pez-Maury and Mario Garc{\'i}a-Dom{\'i}nguez and Francisco J. Florencio and Jos{\'e} C. Reyes},
  journal={Molecular Microbiology},
  year={2002},
  volume={43}
}
In the cyanobacterium Synechocystis sp. PCC 6803, genes for Ni2+, Co2+, and Zn2+ resistance are grouped in a 12 kb gene cluster. The nrsBACD operon is composed of four genes, which encode proteins involved in Ni2+ resistance. Upstream from nrsBACD, and in opposite orientation, a transcription unit formed by the two genes rppA and rppB has been reported previously to encode a two‐component signal transduction system involved in redox sensing. In this report, we demonstrate that rppA and rppB… 
A Two-component Signal Transduction Pathway Regulates Manganese Homeostasis in Synechocystis 6803, a Photosynthetic Organism*
TLDR
Data suggest that the ManS/ManR two-component system plays a central role in the homeostasis of manganese in Synechocystis 6803 cells.
Gene expression under low-oxygen conditions in the cyanobacterium Synechocystis sp. PCC 6803 demonstrates Hik31-dependent and -independent responses.
TLDR
It is suggested that Hik31 helps to regulate growth and overall cellular homeostasis and regulates an important series of genes that relate to energy production and growth and that help to determine how Synechocystis responds to changes in O2 conditions.
Global Transcriptional Profiles of the Copper Responses in the Cyanobacterium Synechocystis sp. PCC 6803
TLDR
The transcriptional responses to copper additions at non-toxic and toxic concentrations in the wild type and in the copper sensitive copR mutant strain suggested that CopRS only controls the expression of copMRS and copBAC operons in response to copper.
Arsenic Sensing and Resistance System in the Cyanobacterium Synechocystis sp. Strain PCC 6803
TLDR
Purified recombinant ArsR protein binds to the arsBHC promoter-operator region in the absence of metals and dissociates from the DNA in the presence of Sb(III) or As(III), suggesting that trivalent metalloids are the true inducers of the system.
Characterization of an Alcohol Dehydrogenase from the Cyanobacterium Synechocystis sp. Strain PCC 6803 That Responds to Environmental Stress Conditions via the Hik34-Rre1 Two-Component System
TLDR
In vitro DNA-protein interaction analysis reveals that the response regulator Rre1 binds specifically to the promoter region of the adhA gene, which encodes a member of the medium-chain alcohol dehydrogenase/reductase family.
Ni interferes in the Cu‐regulated transcriptional switch petJ/petE in Synechocystis sp. PCC 6803
TLDR
It is shown that Ni can act similarly to Cu in inducing petE and repressing petJ, thus leading to a partial switch between cytochrome c6 and plastocyanin, which is essential for growth under conditions of excess Ni.
Characterization of the activity of heavy metal-responsive promoters in the cyanobacterium Synechocystis PCC 6803.
TLDR
It is concluded that due to the largely unspecific heavy metal response of the studied genes only nrsB and arsB are potential candidates for biosensing applications for detection of Ni2+ and arsenic pollutants, respectively.
The CopRS Two-Component System Is Responsible for Resistance to Copper in the Cyanobacterium Synechocystis sp. PCC 68031[C][W][OA]
TLDR
It is shown that the CopRS two-component system is essential for copper resistance in Synechocystis sp.
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