A twist in anti-inflammation: annexin 1 acts via the lipoxin A4 receptor.

@article{Gavins2005ATI,
  title={A twist in anti-inflammation: annexin 1 acts via the lipoxin A4 receptor.},
  author={F N E Gavins and Prescilla Sawmynaden and Bristi E Chatterjee and Mauro Perretti},
  journal={Prostaglandins, leukotrienes, and essential fatty acids},
  year={2005},
  volume={73 3-4},
  pages={211-9}
}
The inflammatory response is a life-saving protective process mounted by the body to overcome pathogen infection and injury; however, in chronic inflammatory pathologies this response can become deregulated. The existence of specialized anti-inflammatory pathways/mediators that operate in the body to down-regulate inflammation have now emerged. Thus, persistence of inflammation leading to pathology could be due to malfunctioning of one or more of these counter-regulatory pathways. Here we focus… CONTINUE READING

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