A twin study of the etiology of prolonged fatigue and immune activation.

  title={A twin study of the etiology of prolonged fatigue and immune activation.},
  author={Ian B. Hickie and Amolak S Bansal and Katherine M Kirk and Andrew R. Lloyd and N. G. Martin},
  journal={Twin research : the official journal of the International Society for Twin Studies},
  volume={4 2},
Risk factors to prolonged fatigue syndromes (PFS) are controversial. Pre-morbid and/or current psychiatric disturbance, and/or disturbed cell-mediated immunity (CMI), have been proposed as etiologic factors. Self-report measures of fatigue and psychologic distress and three in vitro measures of CMI were collected from 124 twin pairs. Crosstwin-crosstrait correlations were estimated for the complete monozygotic (MZ; 79 pairs) and dizygotic (DZ; 45 pairs) twin groups. Multivariate genetic and… CONTINUE READING
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