A tutorial on pilot studies: the what, why and how

@inproceedings{Thabane2010ATO,
  title={A tutorial on pilot studies: the what, why and how},
  author={Lehana Thabane and Jinhui Ma and Rong Chu and Ji Emmy Cheng and Afisi S Ismaila and Lorena P Rios and Reid Robson and Marroon Thabane and Lora M Giangregorio and Charlie H. Goldsmith},
  booktitle={BMC medical research methodology},
  year={2010}
}
Pilot studies for phase III trials - which are comparative randomized trials designed to provide preliminary evidence on the clinical efficacy of a drug or intervention - are routinely performed in many clinical areas. Also commonly know as "feasibility" or "vanguard" studies, they are designed to assess the safety of treatment or interventions; to assess recruitment potential; to assess the feasibility of international collaboration or coordination for multicentre trials; to increase clinical… CONTINUE READING
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