A tryptophan hydroxylase 2 gene polymorphism is associated with panic disorder.

@article{Kim2009ATH,
  title={A tryptophan hydroxylase 2 gene polymorphism is associated with panic disorder.},
  author={Yong Ku Kim and Heon-Jeong Lee and Jong-Chul Yang and Jung-A Hwang and Ho-kyoung Yoon},
  journal={Behavior genetics},
  year={2009},
  volume={39 2},
  pages={170-5}
}
Panic disorder (PD) is a complex and heterogeneous psychiatric condition. Dysfunction within the serotonergic system has been hypothesized to play an important role in PD. The novel brain-specific serotonin synthesizing enzyme, tryptophan hydroxylase 2 (TPH2), which represents the rate-limiting enzyme of serotonin production in the brain, may therefore be of particular importance in PD. We investigated the TPH2 703G/T SNP for association with PD. Patients with PD (n = 108), and control subjects… CONTINUE READING
32 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

Similar Papers

Loading similar papers…