A truncated hepatitis E virus ORF2 protein expressed in tobacco plastids is immunogenic in mice.

@article{Zhou2006ATH,
  title={A truncated hepatitis E virus ORF2 protein expressed in tobacco plastids is immunogenic in mice.},
  author={Yuan-Xiang Zhou and Maggie Yuk-Ting Lee and James Ming-Him Ng and M. -L. Chye and Wing-Kin Yip and S. -Y. Zee and E W -F Lam},
  journal={World journal of gastroenterology},
  year={2006},
  volume={12 2},
  pages={306-12}
}
AIM To cost-effectively express the 23-ku pE2, the most promising subunit vaccine encoded by the E2 fragment comprising of the 3'-portion of hepatitis E virus (HEV) open reading frame 2 (ORF2) in plastids of tobacco (Nicotiana tabacum cv. SR1), to investigate the transgene expression and pE2 accumulation in plastids, and to evaluate the antigenic effect of the plastid-derived pE2 in mice. METHODS Plastid-targeting vector pRB94-E2 containing the E2 fragment driven by rice psbA promoter was… CONTINUE READING
13 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…