A truly simultaneous combination of functional transcranial Doppler sonography and H(2)(15)O PET adds fundamental new information on differences in cognitive activation between schizophrenics and healthy control subjects.

@article{Sabri2003ATS,
  title={A truly simultaneous combination of functional transcranial Doppler sonography and H(2)(15)O PET adds fundamental new information on differences in cognitive activation between schizophrenics and healthy control subjects.},
  author={Osama Sabri and Ammar Owega and Mathias Schreckenberger and L{\'a}szl{\'o} Sturz and Bruno Fimm and Philipp Kunert and Philipp T. Meyer and Dirk Sander and J{\"u}rgen Klingelh{\"o}fer},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2003},
  volume={44 5},
  pages={
          671-81
        }
}
  • O. Sabri, A. Owega, J. Klingelhöfer
  • Published 1 May 2003
  • Psychology, Medicine
  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine
UNLABELLED Working memory deficits are a cardinal feature of the pathophysiology of schizophrenia. Lesion studies and functional blood flow-dependent imaging methods with coarse temporal resolution, such as PET and functional MRI (fMRI), tend to paint a fairly static picture of the cortical regions involved. In contrast, functional transcranial Doppler sonography (fTCD) provides a high temporal resolution. Truly simultaneous fTCD-fMRI is not yet possible for technical reasons, but H(2)(15)O PET… 
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TLDR
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TLDR
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Through a Glass Darkly: Schizophrenia and Functional Brain Imaging
TLDR
Modularity can be assessed by large-scale meta-analyses of neuroimaging studies, illustrated here through the on-line database, Brainmap, and the apparent association of WM and prefrontal cortex fades when one considers all areas engaged in WM, and all tasks associated with cortex.
Feasibility of transcranial Doppler and single photon emission computed tomography in compound neuroactivation task
TLDR
Comparison of TCD and SPECT showed TCD to be inadequately sensitive method for evaluation of cerebral blood flow during complex activation paradigm, demonstrating that both methods partially measure similar cerebralBlood flow changes that occur during neuroactivation.
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