A tripartite organization of the urbilaterian brain: developmental genetic evidence from Drosophila.

@article{Reichert2005ATO,
  title={A tripartite organization of the urbilaterian brain: developmental genetic evidence from Drosophila.},
  author={Heinrich Reichert},
  journal={Brain research bulletin},
  year={2005},
  volume={66 4-6},
  pages={491-4}
}
Developmental genetic studies suggest that the embryonic vertebrate brain has a tripartite ground plan consisting of a forebrain/midbrain, a hindbrain, and an intervening midbrain/hindbrain boundary region, which are characterized by the specific expression of the Otx, Hox and Pax-2/5/8 genes. Recent studies in Drosophila reveal similarities in the expression and function of these genes in patterning the embryonic brains of flies and vertebrates. Thus, in Drosophila, as is vertebrates, a Pax2/5… CONTINUE READING

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