A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease.

@article{Pfeffer2009ATO,
  title={A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease.},
  author={Marc A. Pfeffer and Emmanuel A Burdmann and Chao-yin Chen and Mark E. Cooper and Dick de Zeeuw and K. Eckardt and Jan M. Feyzi and Peter Ivanovich and Reshma Kewalramani and Andrew S. Levey and Eldrin F. Lewis and Janet B. McGill and John J V McMurray and Patrick S Parfrey and H Parving and Giuseppe Remuzzi and Ajay K. Singh and Scott D. Solomon and Robert M Toto},
  journal={The New England journal of medicine},
  year={2009},
  volume={361 21},
  pages={
          2019-32
        }
}
BACKGROUND Anemia is associated with an increased risk of cardiovascular and renal events among patients with type 2 diabetes and chronic kidney disease. Although darbepoetin alfa can effectively increase hemoglobin levels, its effect on clinical outcomes in these patients has not been adequately tested. METHODS In this study involving 4038 patients with diabetes, chronic kidney disease, and anemia, we randomly assigned 2012 patients to darbepoetin alfa to achieve a hemoglobin level of… CONTINUE READING

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