A triad of telomerase, androgen receptor and early growth response 1 in prostate cancer cells.


Telomerase activation is one of the key mechanisms that allow cells to bypass replicative senescence. Telomerase activity is primarily regulated at the level of transcription of its catalytic unit- hTERT. Prostate cancer (PCa), akin to other cancers, is characterized by high telomerase activity. Existing data suggest that hTERT expression and telomerase… (More)
DOI: 10.1080/15384047.2016.1156255


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