A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics.

@article{McCracken2010ATA,
  title={A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics.},
  author={Mandy L. McCracken and Cecilia M Borghese and James R. Trudell and R. Adron Harris},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2010},
  volume={335 3},
  pages={600-6}
}
Alcohols and inhaled anesthetics enhance the function of GABA(A) receptors containing α, β, and γ subunits. Molecular analysis has focused on the role of the α subunits; however, there is evidence that the β subunits may also be important. The goal of our study was to determine whether Asn265, which is homologous to the site implicated in the α subunit… CONTINUE READING