A translatable molecular approach to determining CD8 T-cell epitopes in TMEV infection.

Abstract

Defining the epitope specificity of CD8+ T cells is an important goal in autoimmune and immune-mediated disease research. We have developed a translational molecular approach to determine the epitope specificity of CD8+ T cells using the Theiler's murine encephalomyelitis virus (TMEV) model of multiple sclerosis (MS). TMEV-specific CD8+ T cells were… (More)
DOI: 10.1016/j.humimm.2008.08.293

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@article{Mcdole2008ATM, title={A translatable molecular approach to determining CD8 T-cell epitopes in TMEV infection.}, author={Jeremiah R. Mcdole and Georgette L. Suidan and Erin L. Boespflug and Jie Cheng and Yi Chen and Istvan Pirko and Aaron Johnson}, journal={Human immunology}, year={2008}, volume={69 11}, pages={805-10} }