A transient mathematical model of oxygen depletion during photodynamic therapy.

@article{Henning1995ATM,
  title={A transient mathematical model of oxygen depletion during photodynamic therapy.},
  author={J. P. Hulsbergen Henning and Ronald L Fournier and James A Hampton},
  journal={Radiation research},
  year={1995},
  volume={142 2},
  pages={221-6}
}
A transient one-dimensional mathematical model is presented to help visualize the qualitative and quantitative effects on inter-capillary tissue undergoing photodynamic therapy (PDT). The model is solved by a Crank-Nicholson finite difference formulation to provide time-dependent concentrations of the Type II mechanism's photo-oxidation species in the tissue surrounding a capillary. The time-dependent solution allows educated decisions to be made as to the optimum timing of light fractionation… CONTINUE READING

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