A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs

@inproceedings{Fulga2015ATR,
  title={A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs},
  author={Tudor A. Fulga and Elizabeth M. McNeill and Richard Binari and Julia Yelick and Alexandra Blanche and Matthew Booker and Bruno R. Steinkraus and Michael Schnall-Levin and Yong Ju Zhao and Todd F. DeLuca and Fernando Bejarano and Zhe Han and Eric C. Lai and Dennis P Wall and Norbert Perrimon and David L Van Vactor},
  booktitle={Nature communications},
  year={2015}
}
Although the impact of microRNAs (miRNAs) in development and disease is well established, understanding the function of individual miRNAs remains challenging. Development of competitive inhibitor molecules such as miRNA sponges has allowed the community to address individual miRNA function in vivo. However, the application of these loss-of-function strategies has been limited. Here we offer a comprehensive library of 141 conditional miRNA sponges targeting well-conserved miRNAs in Drosophila… CONTINUE READING
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