A transcriptome signature distinguished sporadic from postradiotherapy radiation-induced sarcomas.

Abstract

Exposure to ionizing radiation is a known risk factor for cancer. However, up to now, rigorously defined scientific criteria that could establish case-by-case the radiation-induced (RI) origin of a tumour have been lacking. To identify genes that could constitute a RI signature, we compared the transcriptome of 12 sarcomas arising in the irradiation field… (More)
DOI: 10.1093/carcin/bgr064

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