A transcriptionally active form of TFIIIC is modified in poliovirus-infected HeLa cells.

Abstract

In HeLa cells, RNA polymerase III (pol III)-mediated transcription is severely inhibited by poliovirus infection. This inhibition is due primarily to the reduction in transcriptional activity of the pol III transcription factor TFIIIC in poliovirus-infected cells. However, the specific binding of TFIIIC to the VAI gene B-box sequence, as assayed by DNase I… (More)

Topics

Cite this paper

@article{Clark1990ATA, title={A transcriptionally active form of TFIIIC is modified in poliovirus-infected HeLa cells.}, author={Melody Clark and Amitava Dasgupta}, journal={Molecular and cellular biology}, year={1990}, volume={10 10}, pages={5106-13} }