A three-plasma miRNA signature serves as novel biomarkers for osteosarcoma.

  title={A three-plasma miRNA signature serves as novel biomarkers for osteosarcoma.},
  author={Liu Ouyang and Ping Liu and Shuhua Yang and Shunan Ye and Weihua Xu and Xianzhe Liu},
  journal={Medical oncology},
  volume={30 1},
Osteosarcoma is the most common human primary malignant bone tumor in children and young adults. Sensitive and non-invasive biomarkers that can facilitate disease detection at early stage are highly desirable to improve survival rate and help to determine optimized treatment for osteosarcoma. The small non-coding RNAs, microRNAs (miRNAs), have recently been identified as critical regulators for various diseases including cancer and may represent a novel class of cancer biomarkers. In this study… CONTINUE READING
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