A three-miRNA signature as promising non-invasive diagnostic marker for gastric cancer

@inproceedings{Shin2015ATS,
  title={A three-miRNA signature as promising non-invasive diagnostic marker for gastric cancer},
  author={Vivian Yvonne Shin and Enders K. O. Ng and Vivian Wai Fung Chan and Ava Kwong and Kent-Man Chu},
  booktitle={Molecular Cancer},
  year={2015}
}
BackgroundDespite the declining incidence of gastric cancer, mortality rate remains high due to late presentation. We aimed to evaluate the sensitivity of miRNA as a diagnostic marker for gastric cancer in the circulation.MethodsPlasma samples from 3 independent groups comprise 123 gastric cancer patients and 111 healthy controls for miRNA profiling from microarray screening.ResultsMicroarray data showed that 25 miRNAs were upregulated in gastric cancer patients and 6 highly expressed miRNAs… CONTINUE READING

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