A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses.

Abstract

The structure and function of kinesin heavy chain from D. melanogaster have been studied using DNA sequence analysis and analysis of the properties of truncated kinesin heavy chain synthesized in vitro. Analysis of the sequence suggests the existence of a 50 kd globular amino-terminal domain that contains an ATP binding consensus sequence, followed by… (More)

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@article{Yang1989ATS, title={A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses.}, author={J. T. Yang and Robert A. Laymon and Lawrence S. B. Goldstein}, journal={Cell}, year={1989}, volume={56 5}, pages={879-89} }