A three-dimensional model of a group II intron RNA and its interaction with the intron-encoded reverse transcriptase.

@article{Dai2008ATM,
  title={A three-dimensional model of a group II intron RNA and its interaction with the intron-encoded reverse transcriptase.},
  author={Lixin Dai and Dinggeng Chai and Shan-Qing Gu and Jesse Gabel and Sergei Yu Noskov and Forrest J H Blocker and Alan M. Lambowitz and Steven Zimmerly},
  journal={Molecular cell},
  year={2008},
  volume={30 4},
  pages={472-85}
}
Group II introns are self-splicing ribozymes believed to be the ancestors of spliceosomal introns. Many group II introns encode reverse transcriptases that promote both RNA splicing and intron mobility to new genomic sites. Here we used a circular permutation and crosslinking method to establish 16 intramolecular distance relationships within the mobile Lactococcus lactis Ll.LtrB-DeltaORF intron. Using these new constraints together with 13 established tertiary interactions and eight published… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

The group II intron maturase: a reverse transcriptase and splicing factor go hand in hand.

Current opinion in structural biology • 2017
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Group II introns: ribozymes that splice RNA and invade DNA

A. M. Pyle, A. M. Lambowitz
In The RNA World, Third Edition, • 2006
View 6 Excerpts
Highly Influenced

A single active-site region for a group II intron

Nature Structural &Molecular Biology • 2005
View 6 Excerpts
Highly Influenced

Antagonistic substrate binding by a group II intron ribozyme.

Journal of molecular biology • 1999
View 5 Excerpts
Highly Influenced

Molecular Cell Group II Intron RNA

R. Saldanha, B. Chen, +3 authors A. M. Lambowitz
Biochemistry • 1999
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…