A third functional isoform enriched in mushroom body neurons is encoded by the Drosophila 14-3-3zeta gene.


14-3-3 proteins are highly conserved across eukaryotes, typically encoded by multiple genes in most species. Drosophila has only two such genes, 14-3-3zeta (leo), encoding two isoforms LEOI and LEOII, and 14-3-3epsilon. We report a bona fide third functional isoform encoded by leo divergent from the other two in structurally and functionally significant… (More)
DOI: 10.1016/j.febslet.2009.08.003