A thermoplastic elastomer patch matrix for traditional Chinese medicine: design and evaluation.

@article{Wang2014ATE,
  title={A thermoplastic elastomer patch matrix for traditional Chinese medicine: design and evaluation.},
  author={Cheng-xiao Wang and Jianfang Ma and Ran Liu and Wei Han and Xiuzhen Tang},
  journal={Drug development and industrial pharmacy},
  year={2014},
  volume={40 2},
  pages={211-21}
}
OBJECTIVE To design and evaluate a novel pressure sensitive adhesive (PSA) patch containing traditional Chinese medicine (TCM) using styrene-isoprene-styrene (SIS) copolymer. METHOD A mixture D-optimal design with ternary response surface diagram was employed in the optimization process. The proportions of SIS copolymer, tackifying resin and plasticizer were selected as the independent variables while tack force, peel strength of the patch and skin penetrability of methyl salicylate were… CONTINUE READING