A theoretical study of the thermal response of skin to cryogen spray cooling and pulsed laser irradiation: implications for treatment of port wine stain birthmarks.

@article{Anvari1995ATS,
  title={A theoretical study of the thermal response of skin to cryogen spray cooling and pulsed laser irradiation: implications for treatment of port wine stain birthmarks.},
  author={Bahman Anvari and Benjamin Tanenbaum and Thomas E. Milner and Sol Kimel and Lars Othar Svaasand and J. Stuart Nelson},
  journal={Physics in medicine and biology},
  year={1995},
  volume={40 9},
  pages={1451-65}
}
The successful treatment of port wine stain (PWS) patients undergoing laser therapy is based on selective thermal coagulation of blood vessels without damaging the normal overlying epidermis. Cryogen spray cooling of skin may offer an effective method for minimizing epidermal thermal injury. Inasmuch as the density of melanosomes and depth of PWS blood vessels can vary considerably, an optimum cooling strategy is required on an individual patient basis. We present a theoretical study of the… CONTINUE READING
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