A theoretical study of the response of vascular tumours to different types of chemotherapy

@article{Panovska2008ATS,
  title={A theoretical study of the response of vascular tumours to different types of chemotherapy},
  author={Jasmina Panovska and Helen M. Byrne and Philip K. Maini},
  journal={Mathematical and Computer Modelling},
  year={2008},
  volume={47},
  pages={560-579}
}
In this paper we formulate and explore a mathematical model to study continuous infusion of a vascular tumour with isolated and combined blood-borne chemotherapies. The mathematical model comprises a system of nonlinear partial differential equations that describe the evolution of the healthy (host) cells, the tumour cells and the tumour vasculature, coupled with distribution of a generic angiogenic stimulant (TAF) and blood-borne oxygen. A novel aspect of our model is the presence of blood… CONTINUE READING
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