A theoretical study of the effect of experimental noise on the measurement of anisotropy in diffusion imaging.

@article{Bastin1998ATS,
  title={A theoretical study of the effect of experimental noise on the measurement of anisotropy in diffusion imaging.},
  author={Mark E. Bastin and Paul A. Armitage and Ian Marshall},
  journal={Magnetic resonance imaging},
  year={1998},
  volume={16 7},
  pages={773-85}
}
Diffusion tensor imaging (DTI) is a modality known to be highly sensitive to the detrimental effects of experimental noise. Here, using Monte Carlo simulations, we compare and contrast how noise complicates the measurement of diffusion anisotropy in diffusion tensor and conventional diffusion-weighted imaging (DWI). As the signal-to-noise ratio (SNR) decreases below a value of approximately 20, the eigenvalues (lambda(i)) of the diffusion tensor D are found to diverge rapidly from their true… CONTINUE READING

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