A theoretical model of Aquifex pyrophilus flagellin: implications for its thermostability.

@article{Malapaka2006ATM,
  title={A theoretical model of Aquifex pyrophilus flagellin: implications for its thermostability.},
  author={Venkata R R Malapaka and Brian C Tripp},
  journal={Journal of molecular modeling},
  year={2006},
  volume={12 4},
  pages={481-93}
}
Aquifex pyrophilus is a flagellated hyperthermophilic eubacterial species that grows optimally at 85 degrees C. The thermostable A. pyrophilus flagellar filament is primarily composed of a single protein called flagellin (FlaA). The N- and C-terminal sequence regions of FlaA are important for self-assembly and share high sequence similarity with mesophilic bacterial flagellins. We have developed a predictive 3D-structure of FlaA, using the published structure of mesophilic Salmonella… CONTINUE READING
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