• DOI:10.1007/s10815-009-9321-y
• Corpus ID: 23967519

A theoretical model for single blastocyst transfer

@article{Teranishi2009ATM,
  title={A theoretical model for single blastocyst transfer},
  author={Akihiro Teranishi and Atsushi Kuwata and T. Fumino and H. Hamai and Minoru Shigeta},
  journal={Journal of Assisted Reproduction and Genetics},
  year={2009},
  volume={26},
  pages={327-334}
}

• A. Teranishi, A. Kuwata, +2 authors M. Shigeta
• Published 14 July 2009
• Medicine
• Journal of Assisted Reproduction and Genetics

ObjectiveTo elucidate the relationship between embryo grade and ART outcomes and determine how to decrease multiple pregnancy rates by assigning patients to single embryo transfer (SET) instead of dual embryo transfer (DET) according to embryo grade and/or availability.DesignRetrospective medical record review.SettingIVF fertility center.Patients247 women undergoing day 5 DET after in vitro fertilization or intracytoplasmic sperm injection treatment.MethodsWe retrospectively investigated embryo grade and outcomes on day 5 DET and calculated theoretical multiple pregnancy rates by assigning patients to SET instead of DET according to a combination of embryo grades and availability.Main Outcomes MeasuresImplantation, pregnancy, multiple pregnancy, expected pregnancy and expected multiple pregnancy rates.ResultsEmbryo grade affects implantation rates so that embryo transfer of at least one embryo with grade ≥ 3BB resulted in high multiple pregnancy rates as well as high pregnancy rates. By performing DET, the clinical pregnancy rate was 39.9% with a multiple pregnancy rate of 33.3%; however, had SET been performed with an embryo graded 3BB or better, theoretical calculated pregnancy rates would have dropped to 35.8% but with a multiple pregnancy rate of 7.2%.ConclusionsOur model showed that cases having at least one embryo with grade ≥ 3BB might serve as suitable candidates for SET.