A theoretical framework for comparing noise characteristics of spectral, differential phase-contrast and spectral differential phase-contrast x-ray imaging

@article{Mechlem2020ATF,
  title={A theoretical framework for comparing noise characteristics of spectral, differential phase-contrast and spectral differential phase-contrast x-ray imaging},
  author={Korbinian Mechlem and Thorsten Sellerer and Manuel Viermetz and Julia Herzen and Franz Pfeiffer},
  journal={Physics in Medicine \& Biology},
  year={2020},
  volume={65}
}
Spectral and grating-based differential phase-contrast (DPC) x-ray imaging are two emerging technologies that offer additional information compared with conventional attenuation-based x-ray imaging. In the case of spectral imaging, energy-resolved measurements allow the generation of material-specific images by exploiting differences in the energy-dependent attenuation. DPC imaging uses the phase shift that an x-ray wave exhibits when traversing an object as contrast generation mechanism… 
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References

SHOWING 1-10 OF 68 REFERENCES
Spectral Differential Phase Contrast X-Ray Radiography
TLDR
A novel material decomposition algorithm is proposed that uses the spectral and the phase contrast information simultaneously simultaneously to determine the (projected) electron density of an X-ray wave when traversing an object.
Analytical evaluation of the signal and noise propagation in x-ray differential phase-contrast computed tomography
TLDR
This work focuses on grating-based differential phase-contrast imaging and derives a mathematical framework that is able to analytically predict the relative performance of both imaging techniques in the sense of the relative contrast-to-noise ratio for the contrast of any two materials.
Noise in x-ray grating-based phase-contrast imaging.
TLDR
The authors used a least squares fitting algorithm to calculate the noise behavior of the three quantities absorption, differential phase, and dark-field image and found that the variance of the reconstructed phase is only dependent of the total number of photons used to generate the phase image and the visibility of the experimental setup.
Cramér-Rao lower bound in differential phase contrast imaging and its application in the optimization of data acquisition systems
Unlike conventional x-ray absorption imaging, x-ray differential phase contrast imaging (DPCI) uses a phase retrieval algorithm to obtain x-ray phase information from a group of x-ray intensity
Beam hardening effects in grating-based x-ray phase-contrast imaging.
TLDR
It is shown that beam hardening leads to a similar reduction of image quality in phase-cont contrast imaging as in conventional attenuation-contrast imaging, and it is demonstrated that for homogeneous objects, beamhardening artifacts can be corrected by a linearization technique, applicable to all kinds of phase- Contrast methods using polychromatic sources.
Dual energy phase contrast x-ray imaging with Talbot-Lau interferometer
In weakly absorbing materials such as polymers and soft tissue, x-ray phase sensitive imaging methods can provide substantially enhanced contrast compared to classical, absorption based radiography.
Direct quantitative material decomposition employing grating-based X-ray phase-contrast CT
TLDR
A new method of ‘virtual dual-energy CT’ employing grating-based phase-contrast for quantitative material decomposition employing signal extraction approach to phase- Contrast data multiplies the diagnostic information gained within a single CT acquisition.
Hard-X-ray dark-field imaging using a grating interferometer.
TLDR
This letter reports a new approach on the basis of a grating interferometer that can efficiently yield dark-field scatter images of high quality, even with conventional X-ray tube sources and is fully compatible with conventional transmission radiography and a recently developed hard-X-ray phase-contrast imaging scheme.
Radiation dose efficiency comparison between differential phase contrast CT and conventional absorption CT.
TLDR
The differential phase contrast CT method provided higher CNR than conventional absorption CT at equivalent dose levels for most of the materials studied, and so may enable achievement of the same object visibility as conventional absorptionCT methods at a lower exposure level.
Inverse geometry for grating-based x-ray phase-contrast imaging
Phase-contrast imaging using conventional polychromatic x-ray sources and grating interferometers has been developed and demonstrated for x-ray energies up to 60 keV. Here, we conduct an analysis of
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