A theoretical and experimental analysis of formulation and device parameters affecting solution MDI size distributions.

@article{Stein2004ATA,
  title={A theoretical and experimental analysis of formulation and device parameters affecting solution MDI size distributions.},
  author={Stephen W. Stein and Paul Myrdal},
  journal={Journal of pharmaceutical sciences},
  year={2004},
  volume={93 8},
  pages={
          2158-75
        }
}
  • S. Stein, P. Myrdal
  • Published 1 August 2004
  • Chemistry, Medicine
  • Journal of pharmaceutical sciences
The influence of formulation and device configurations on the initial droplet and residual particle size distribution from solution MDIs was theoretically and experimentally examined. Aerodynamic size distribution tests were conducted to characterize the size distribution of the residual particles formed when a solution MDI is actuated. The measured size distributions were approximately log-normally distributed, and did not show evidence of a secondary large particle mode. Theoretical… 
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  • Medicine, Chemistry
    AAPS PharmSciTech
  • 2007
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TLDR
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