A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus.

  title={A tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus.},
  author={M J Lee and D. Y. Jeong and Won Sin Kim and Harold D. Kim and Chung Ho Kim and Won Wo Park and Yong-Ho Park and Kwang Sang Kim and Hwan Mook Kim and Dae Shick Kim},
  journal={Applied and environmental microbiology},
  volume={66 4},
Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced TTX, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the… CONTINUE READING
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