A tetrazolato-bridged dinuclear platinum(II) complex exhibits markedly high in vivo antitumor activity against pancreatic cancer.

Abstract

Some platinum(II) coordination complexes are effective anticancer agents. cis-Diamminedichloridoplatinum(II) (cisplatin), a mononuclear platinum(II) complex, is one of the most commonly used anticancer drugs. Although platinum-based chemotherapy can cause serious side effects, its efficacy has prompted the design and synthesis of next-generation anticancer… (More)
DOI: 10.1002/cmdc.201100141

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