A test for the statistical significance of DNA sequence similarities for application in databank searches

@article{Mott1989ATF,
  title={A test for the statistical significance of DNA sequence similarities for application in databank searches},
  author={R. F. Mott and T. B. Kirkwood and R. N. Curnow},
  journal={Computer applications in the biosciences : CABIOS},
  year={1989},
  volume={5 2},
  pages={123-31}
}
A method is developed, based on word-searching, which provides a rapid test for the statistical significance of DNA sequence similarities for use in databank searching. The method makes allowance for the lengths and dinucleotide compositions of the sequences being compared. A way is also described to calculate the power of the test, i.e. the probability of… CONTINUE READING